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UEFA Europa League - Lyon VS Manchester United Prediction

UEFA Europa League - Lyon VS Manchester United Prediction
UEFA Europa League  -  Lyon VS Manchester United
Match Time:11-04-2025 03:00 Friday (GMT+8)
Football Livescore | Match Prediction & Tips

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Lyon
Paulo Fonseca has a new injury concern hampering his preparations ahead of his side’s latest fixture. The Lyon manager might be bereft of the services of two first-team players vs Manchester United on Thursday.

Ernest Nuamah is the latest absentee after picking up an ACL injury this past weekend against LOSC Lille. The Ghanaian international has joined Malick Fofana (knee) on the sidelines. Meanwhile, Fonseca will be wary of possible suspensions, with Alexandre Lacazette, Ainsley Maitland-Niles, Moussa Niakhate, and Corentin Tolisso walking the tightrope.

Lucas Perri should take his spot between the sticks, with Lyon lining up in a 4-2-3-1 formation in front of him vs Manchester United on Thursday. The backline will likely feature Ainsley Maitland-Niles, Clinton Mata, Moussa Niakhate, and Nicolas Tagliafico.

As for the midfield unit, Nemanja Matic will likely pair up with Tanner Tessmann in the double pivot, with Corentin Tolisso reprising the no. 10 role. Finally, Georges Mikautadze will lead the line for Lyon against Manchester United, with Rayan Cherki and Thiago Almada completing the numbers in the offensive unit.

Manchester United
Unlike his counterpart in the Lyon dugout, Ruben Amorim has no new issues to worry about ahead of the trip to Parc Olympique Lyonnais. The Manchester United manager might be without as many as seven first-team players.

While Toby Collyer (muscular) and Kobbie Mainoo (calf) are close to returning, Thursday’s game might have come too soon for the duo. However, Matthijs de Ligt (foot), Jonny Evans (lower back), Ayden Heaven (ankle), Lisandro Martinez (knee), and Amad (ankle) remain on the sidelines.

Andre Onana is the automatic pick between the sticks, with Manchester United lining up in a 3-4-2-1 formation in front of him vs Lyon on Thursday. The central defensive unit will feature Noussair Mazraoui, Harry Maguire, and Leny Yoro. Diogo Dalot and Patrick Dorgu will start as the two wing-backs.

The wide duo will provide width in the final third and support the centre-backs. As for the midfield unit, the resurgent Casemiro should pair up with Manuel Ugarte in the middle of the park. Finally, Joshua Zirkzee will spearhead the Manchester United attack against Lyon, with Alejandro Garnacho and Bruno Fernandes providing creative support.

Lyon possible starting lineup:
Perri; Maitland-Niles, Mata, Niakhate, Tagliafico; Tessmann, Matic; Cherki, Tolisso, Almada; Mikautadze

Manchester United possible starting lineup:
Onana; Mazraoui, Maguire, Yoro; Dalot, Ugarte, Casemiro, Dorgu; Fernandes, Garnacho; Zirkzee

Lyon vs Manchester United Head-to-Head and Key Numbers
Manchester United have a good record against Lyon on the European stage and have won two out of the four matches played between the two teams, with the other two matches ending in draws.
Lyon are winless in their four matches against Manchester United in major European competitions - they have only faced Barcelona on more occasions without a victory on the European stage.
Manchester United have played both their European games away from home against Lyon in the UEFA Champions League and pulled off a comeback to secure a draw on both occasions.
Lyon defeated FCSB by a 4-0 scoreline in the round of 16 this season - their largest margin of victory in the UEFA Champions League since 2017.
Manchester United have lost only one of their last 21 matches in the UEFA Europa League.

Prediction: Lyon 1-1 Manchester United
While at least three goals have been scored in each off Lyon's last four matches, Man United's recent games have been tighter with more than three goals scored in just two of their last seven fixtures, making Thursday's encounter a difficult one to predict. Lyon are enjoying a better run of form at present and have particularly excelled on home soil, but they have looked vulnerable at times at the back, while Man United have had success in the Europa League this term so they may find a way to claim at least a share of the spoils to keep the tie nicely poised ahead of the second leg at Old Trafford.
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